Individuals who received a solid organ transplant in the United States were followed up annually on the anniversary of the transplant date for an assessment of their health status. These data were recorded in the Scientific Registry of Transplant Recipients (SRTR). All analyses presented are limited to adults aged 20 years or older at the time of their first organ transplant. Diabetes status (type 1 or 2) and hypertension status are as listed at the time of transplant. For all transplant recipients, use of calcineurin inhibitors (CNI) to prevent transplant rejection is presented as many of these medications have been shown to be nephrotoxic¹. The recording of data in the SRTR pertaining to CKD/kidney function varied by organ type and is discussed below.

Liver transplant data included serum creatinine measurements for each follow-up but do not report whether patients went on dialysis or had a kidney transplant since their last visit. A liver transplant recipient is defined as having CKD or ESRD if he/she has Chronic Kidney Disease Epidemiolgy Collaboration (CKD-EPI) equation estimated GFR <60 ml/min/1.73 m². Donor type (deceased vs. living) information is provided for liver transplant recipients.

¹Ojo AO. Renal disease in recipients of nonrenal solid organ transplantation. Semin Nephrol.2007;27(4):498-507.