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Assisted Reproductive Technology (ART) Data

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Colorado Center for Reproductive Medicine

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Clinic Services & Profile
Patient & Cycle Characteristics
Success Rates: Patients Using Own Eggs
Success Rates: Patients Using Donor Eggs
Clinic Data Summary

Colorado Center for Reproductive Medicine
10290 RidgeGate Cir
Lone Tree, Colorado 80124
Phone: (303) 788-8300

Medical Director
William B. Schoolcraft, MD

Clinic Profile
Clinic Service & Profile

Donor egg services	Yes
Donor embryo services	Yes
Embryo cryopreservation services	Yes
Egg cryopreservation services	Yes
Gestational carrier services	Yes
SART member	Yes
Verified lab accreditation	Yes

Clinic Summary
2019 Clinic Summary	Number
Total cycles	3638
Fertility preservation cycles	440
Pregnancies	1270
Deliveries	1090
Total infants born	1194

Patient and cycle characteristics summarize the types of ART services performed and the kinds of patients who received ART procedures. Please note patient characteristics are presented per cycle rather than per patient. As a result, patients who had more than one ART cycle within the reporting year are represented more than once.

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Because a woman's fertility declines with age, ART data are reported separately by age group. You may wish to find a clinic that commonly sees patients your age.

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What were the ages of patients who used ART?

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Clinic information based on 3,638 ART cycles.

View clinic success rates for patients using their own eggs. Results are presented by age of the woman. Results can be filtered by diagnosis and patients with no prior ART use.

Type
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An intended egg retrieval is ART cycle that starts with the intent to retrieve eggs. If eggs are retrieved, it may take one or more transfers to achieve live birth. The cumulative (or combined) chance of a live birth delivery typically increases with each additional egg or embryo transfer because it provides another opportunity to conceive a child. Displayed below are cumulative percentages of intended egg retrievals that resulted in a live birth delivery after all associated egg or embryo transfers within 12 months of cycle start. A live birth delivery is the delivery of one or more infants (e.g. single, twins, triplets) with any signs of life.

Diagnosis

No filterF009

Male factorF006

EndometriosisF005

Tubal factorF001

Ovulatory dysfunctionF003

Uterine factorF002

Diminished ovarian reserveF004

Recurrent pregnancy lossF007

Unexplained factorF008

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Patients using donor eggs/embryos

What was the percentage of intended egg retrievals that resulted in live-birth deliveries?

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No cycles meeting this criterion were reported

Patients using their own eggs

What was the percentage of intended egg retrievals that resulted in live-birth deliveries?

Filter: Diagnosis - No filter

No cycles meeting this criterion were reported

Patients with no prior ART using their own eggs

What was the percentage of intended egg retrievals that resulted in live-birth deliveries?

Filter: Diagnosis - No filter

No cycles meeting this criterion were reported

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View clinic success rates for patients using donor eggs. Results are presented by egg/embryo type. Results can be filtered by diagnosis.

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Displayed below are the percentages of transfers with at least one donor egg or embryo that resulted in live-birth deliveries. A live-birth delivery is the delivery of one or more infants (e.g. single, twins, triplets) with any signs of life.

Diagnosis

No filterF009

Male factorF006

EndometriosisF005

Tubal factorF001

Ovulatory dysfunctionF003

Uterine factorF002

Diminished ovarian reserveF004

Recurrent pregnancy lossF007

Unexplained factorF008

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Patients using donor eggs/embryos

What was the percentage of embryo transfers that resulted in live-birth deliveries?

Filter: Diagnosis - No filter

No cycles meeting this criterion were reported

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DISCLAIMER: Patient medical characteristics, such as age, diagnosis, and ovarian reserve, affect the success of ART treatment. Comparison of success rates across clinics may not be meaningful due to differences in patient populations and ART treatment methods. The success rates displayed here do not reflect any one patient’s chance of success. Patients should consult with a doctor to understand their chance of success based on their own characteristics.

Data Verified By: William B. Schoolcraft, MD
Cumulative Success Rates for ART Intended Retrievals Among Patients Using Their Own Eggs: All Patients (with or without prior ART cycles)^a,b,c

All patients (with or without prior ART cycles)	<35	35-37	38-40	>40
Number of intended retrievals	401	344	382	378
Average number of intended retrievals per live-birth delivery	1.7	1.9	3.0	7.7
Percentage of intended retrievals resulting in live-birth deliveries	60.1%	52.6%	33.2%	13.0%
Percentage of intended retrievals resulting in singleton live-birth deliveries	46.4%	44.2%	26.7%	11.4%
Number of retrievals	390	324	354	351
Percentage of retrievals resulting in live-birth deliveries	61.8%	55.9%	35.9%	14.0%
Percentage of retrievals resulting in singleton live-birth deliveries	47.7%	46.9%	28.8%	12.3%
Number of transfers	343	276	196	79
Percentage of transfers resulting in live-birth deliveries	70.3%	65.6%	64.8%	62.0%
Percentage of transfers resulting in singleton live-birth deliveries	54.2%	55.1%	52.0%	54.4%

New patients (with no prior ART cycles)	<35	35-37	38-40	>40
Percentage of new patients having live-birth deliveries after 1 intended retrieval	66.8%	57.9%	40.9%	16.0%
Percentage of new patients having live-birth deliveries after 1 or 2 intended retrievals	69.7%	60.1%	45.3%	17.0%
Percentage of new patients having live-birth deliveries after all intended retrievals	71.4%	61.8%	49.6%	18.9%
Average number of intended retrievals per new patient	1.1	1.2	1.4	1.6
Average number of transfers per intended retrieval	0.9	0.8	0.5	0.2

Non-cumulative Success Rates for ART Transfers Among Patients Using Eggs or Embryos from a Donor^a,b,c,d

Success Rates for ART Transfers Among Patients Using Eggs or Embryos from a Donor	Fresh embryos fresh eggs	Fresh embryos frozen eggs	Frozen embryos	Donated embryos
Number of transfers	6	*	193	13
Percentage of transfers resulting in live-birth deliveries	5 / 6	* / *	63.7%	9 / 13
Percentage of transfers resulting in singleton live-birth deliveries	5 / 6	* / *	58.0%	8 / 13

Characteristics of ART Cycles ^a,b

Characteristics of ART Cycles	<35	35-37	38-40	>40	Total
Total number of cycles	959	925	899	855	3,638
Percentage of intended egg retrieval cycles without any eggs retrieved (e)	4.0%	2.9%	2.7%	8.8%	4.6%
Percentage of cycles discontinued after retrieval and before transfer or banking (f)	2.0%	4.4%	5.8%	9.3%	5.2%
Percentage of cycles for fertility perservation	11.9%	13.9%	13.7%	8.7%	12.1%
Percentage of transfers using a gestational carrier	3.9%	4.4%	7.7%	12.7%	7.0%
Percentage of transfers using frozen embryos	94.2%	98.7%	98.8%	98.5%	97.5%
Percentage of transfers of at least 1 embryo with ICSI	92.4%	90.2%	85.4%	73.4%	85.8%
Percentage of transfers of at least 1 embryo with PGT	77.7%	88.0%	89.9%	88.3%	85.8%

Clinic Current Services & Profile

Donor Eggs?	Yes
Donated embryos?	Yes
Embryo cryopreservation?	Yes
Egg cryopreservation?	Yes
Gestational carriers?	Yes
SART member?	Yes
Verified lab accreditation?	Yes

Reason for Using ART^a,b,g

Male factor	30%
Endometriosis	6%
Tubal factor	5%
Ovulatory dysfunction	8%
Uterine factor	8%
PGT	4%
Gestational carrier	1%
Diminished ovarian reserve	37%
Egg or embryo banking	52%
Recurrent pregnancy loss	9%
Other, infertility	55%
Other, non-infertility	26%
Unexplained	8%

ART = Assisted Reproductive Technology; ICSI = intracytoplasmic sperm injection; PGT = preimplantation genetic testing (diagnosis or screening)
^a Numbers and percentages exclude 1 cycle(s) that were evaluating new procedures.
^b Fractions are used when the denominator is less than 20. Reported sample size of 1 through 4 have been suppressed due to small sample size.
^c A live birth is defined as the delivery of one or more infants with any sign of life. Multiple-infant births (for example, twins) with at least one live born infant are counted as one live birth. Success rates for cycles using a patient's own eggs are calculated by using all cycles started in 2018 with intent to retrieve a patients's eggs and all transfers of these eggs, or embryos created from these eggs, started within 12 months of the start of the retrieval cycle. Success rates for cycles using a donor's eggs or donated embryos are calculated by using all transfers started in 2019.
^d Patients of all ages are combined because previous data show that a patient’s age does not substantially affect success when using a donor’s eggs or donated embryos.
^e Includes cycles in which no eggs were retrieved among all cycles in which egg retrieval was expected.
^f Includes cycles in which no eggs or embryos were transferred or frozen, among all cycles in which eggs were retrieved and all frozen cycles.
^g Reasons may add to more than 100% because more than one diagnosis can be reported for each ART cycle.

Description of Services and Profile

Description of Services and Profile
Donor egg services	A donor egg cycle occurs when an embryo is formed from the egg of one woman (the donor) and is transferred to another woman (the recipient).
Donor embryo services	A donor embryo is an embryo that is donated by a patient or couple who previously underwent ART treatment and had extra embryos available.
Embryo cryopreservation services	Cryopreservation is the practice of freezing embryos for potential future use.
Egg cryopreservation services	Cryopreservation is the practice of freezing eggs for potential future use.
Gestational carrier services	A gestational carrier or surrogate is a woman who gestates, or carries, an embryo that was formed from the egg of another woman. The surrogate usually has a contractual obligation to return the infant to its intended parents.
SART member	The Society of Assisted Reproductive Technology (SART) is an affiliate of the American Society for Reproductive Medicine (ASRM) and is a professional society composed of clinics and programs that provide ART.
Verified lab accreditation	A “Yes” indicates the clinic had an embryo laboratory accreditation at the time of reporting by at least one of specified accrediting organizations.

Clinic Summary

Description of Clinic Summary
Total cycles	Because ART consists of several steps, an ART procedure is typically referred to as a cycle of treatment rather than a procedure at a single point in time. The start of an ART cycle is usually when a woman begins taking medication to stimulate egg production or begins monitoring with the intent of having embryos transferred. This is the number of ART cycles started. The total number of ART cycles is calculated as the sum of (1) the number of cycles started with the intent to freeze all resulting eggs or embryos (for example, short term banking or fertility preservation); (2) the number of cycles started with the intent to transfer fresh or frozen eggs retrieved from either the patient or donor; and (3) the number of cycles started with the intent to transfer fresh or frozen embryos created from fresh or frozen eggs retrieved from either the patient or donor.
Fertility Preservation cycles	The number of cycles started with the intent of freezing and banking all eggs or embryos for at least 12 months for future use; * Reported sample size of 1 through 4 have been suppressed.
Pregnancies	The total number of pregnancies that resulted from ART cycles. Because some pregnancies end in a miscarriage or stillbirth, the number of pregnancies may be higher than the number of deliveries or infants born.
Deliveries	The total number of live birth deliveries of infants conceived with the help of ART. One delivery could result in one or more infants born.
Total infants born	The total number of ART-conceived infants born, including single infants and infants born in a multiple birth delivery (e.g., twins, triplets).

Filter & Description &

Filter and Description
Filter	Description
No filter	Multiple female factor infertility is a diagnostic category used when more than one female cause of infertility but no male factor infertility is diagnosed.
Male factor	Male factor infertility refers to any cause of infertility due to low sperm count or problems with sperm function that makes it difficult for a sperm to fertilize an egg under normal conditions.
Endometriosis	Endometriosis is a medical condition that involves the presence of tissue similar to the uterine lining in abnormal locations. This condition can affect both fertilization of the egg and embryo implantation.
Tubal factor	Tubal factor infertility is a diagnostic category used when the woman’s fallopian tubes are blocked or damaged, making it difficult for the egg to be fertilized or for an embryo to travel to the uterus.
Ovulatory dysfunction	Ovulatory dysfunction is a diagnostic category used when a woman’s ovaries are not producing eggs normally. It includes polycystic ovary syndrome and multiple ovarian cysts.
Uterine factor	Uterine factor infertility is a structural or functional disorder of the uterus that results in reduced fertility.
Diminished ovarian reserve	Diminished ovarian reserve means that the ability of the ovary to produce eggs is reduced. Reasons include congenital, medical, surgical causes, or advanced age.
Recurrent pregnancy loss	Other causes of infertility include immunological problems, chromosomal abnormalities, cancer chemotherapy, and serious illnesses.
Unexplained factor	Unknown cause of infertility is a diagnostic category used when no cause of infertility is found in either the woman or the man.

Cycle Type

Cycle Types
Cycle Type	Description
Patients using their own eggs	Own ART cycles are those cycles in which a woman's own embryos are transferred to the woman.

• HHS Office on Women's Health	• Society for Assisted Reproductive Technology (SART)	• American Society for Reproductive Medicine (ASRM)
• Resolve	• Path 2 Parenthood

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