Prevalence refers to the presence of a health-related condition (e.g., CKD) in a particular population at a specific point in time (point prevalence) or, less frequently, during a specific period (period prevalence); it may be expressed as a count (number of prevalent cases) or as the proportion of cases in the population (prevalence of the condition).

Without awareness and knowledge of chronic kidney disease (CKD in the general and medical communities, the burden of CKD (prevalence and incidence) cannot be diminished. Early awareness of CKD could slow progression to kidney failure and mitigate associated complications and outcomes.

Identification of those at risk for development of CKD forms an integral part of a CKD surveillance system. First, examining changes in the burden of risk factors for CKD can help predict the potential future burden of CKD. For example, if the prevalence of an important risk factor is rising, it is likely that the prevalence of CKD will rise accordingly. Second, assessing the burden of risk factors can also help identify which interventions are likely to have the most impact on reducing the burden of CKD. Early intervention in those with risk factors may help prevent or delay the onset of CKD, or in the case of established CKD, help slow progression or reduce related morbidity and mortality.

CKD is characterized by a high burden of comorbidities such as cardiovascular disease, obesity, diabetes, hypertension, and others. Many of these conditions can be both a cause and consequence of CKD. In the presence of CKD, outcomes among patients with other comorbidities are typically worse than in the absence of CKD.  The most important consequences of CKD include renal disease progression that has the potential to lead to end stage renal disease (ESRD), or death.

Assessment of the processes of care and practice patterns related to the detection and management of CKD is an integral part of a national CKD surveillance system. Tracking the processes of care related to CKD could be instrumental in facilitating the implementation of early diagnostic steps and institution of appropriate therapies to either prevent the development of disease or slow progression of established disease. Examination of administrative health care data is a cost-efficient method for tracking processes of care in the practice setting.

Improvements in population health rely on a strong health care system to deliver quality care and prevention services. Indicators in this section monitor the capacity for service delivery, health care workforce, and health care financing related to kidney disease. Examples include health insurance coverage, number of primary care physicians and nephrologists, laboratory reporting of estimated glomerular filtration rate, and the availability of transplant centers and dialysis facilities.