The prevalence of restless leg syndrome (RLS) was significantly higher in children with CKD than in healthy children (15.3% vs. 5.9%; P= 0.04).
Chart Explanation: The prevalence of RLS was determined for a cohort of both healthy children and those with CKD. The prevalence of RLS was significantly higher in children with CKD than in healthy children (15.3% vs. 5.9%; P= 0.04). RLS was defined using criteria from the National Institutes of Health and was assessed using a diagnostic questionnaire that accounted for the exclusion of mimics. The healthy patients were from two pediatric practices in Atlanta and the pediatric CKD patients were recruited from outpatient clinics at Children’s Health Care of Atlanta.
A cross-sectional cohort study comprises children aged 8 to 18 years, living in the the metropolitan area of Atlanta. The control participants were recruited from two pediatric practices in Atlanta, while the participants with CKD were recruited from outpatient clinics and the hemodialysis unit at Children’s Health Care of Atlanta. The goal of the study was to compare the prevalence of restless leg syndrome (RLS) between children with CKD and healthy controls. Participants in the CKD group had either a functioning transplant, were on dialysis, or had an eGFR less than 60 mL/min/1.73 m
2.
This indicator is based upon analysis in published literature: Riar SK, Leu RM, Turner-Green TC, et al. Restless legs syndrome in children with chronic kidney disease.
Pediatr Nephrol. 2013;28(5):773-795.
http://www.ncbi.nlm.nih.gov/pubmed/23334386
| Field | Data |
|---|
|
| Description of Measure | Prevalence of restless legs syndrome (RLS) |
|---|
| Data Source | Atlanta pediatric clinics and the hemodialysis unit at Children's Health Care of Atlanta |
|---|
| Type of Data Source | Private |
|---|
| Data Set | Children aged 8 to 18 years, living in the the metropolitan area of Atlanta; the control participants were recruited from two pediatric practices in Atlanta, while the participants with CKD were recruited from outpatient clinics and the hemodialysis unit at Children’s Health Care of Atlanta |
|---|
| Health Care Data System | No |
|---|
| Regional or National? | Regional |
|---|
| Demographic group | Children aged 8 to 18 years, living in the the metropolitan area of Atlanta: 85 control participants from two pediatric practices in Atlanta; 124 participants with CKD recruited from outpatient clinics and the hemodialysis unit at Children’s Health Care of Atlanta. |
|---|
| Numerator | All participants with restless legs syndrome |
|---|
| Denominator | All participants |
|---|
| Definition of CKD | eGFR of <60 mL/min/1.73 m2; cases also included patients with a functioning kidney transplant, patients receiving peritoneal dialysis or hemodialysis |
|---|
| Primary Data Source Indicator | Prevalence of RLS |
|---|
| Primary Indicator Method of Measurement | An RLS diagnostic questionnaire that was developed using the NIH consensus guidelines; pediatric questions were incoporated from the Peds REST study. |
|---|
| Secondary Data Source Indicator | Presence of CKD |
|---|
| Secondary Indicator Method of Measurement | Used eGFR values previously entered in patients' medical records |
|---|
| Frequency of Measurement (Primary) | Once |
|---|
| Period Currently Available | 2012 |
|---|
| Pending Data | None |
|---|
| U.S. Regions Covered by Primary Variable | Communities in Atlanta, Georgia |
|---|
| Additional Data Items of Interest | Stratification variables of interest (BMI, age, race, gender, stage of CKD) |
|---|
| Limitations of Indicator | Small sample size may have led to false-negative results; gender and racial differences between the control and patient populations |
|---|
| Analytical Considerations | Cases and controls were well-matched for age |
|---|