Indicator Details: Reporting Convention Used Among Laboratories Reporting eGFRa
Data Sources
 
Stratification and Year Choices:

  Source
  • NKDEP

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Published literature or one-time analysis, ongoing surveillance not available Published literature or one-time analysis, ongoing surveillance not available

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Footnotes:
a MDRD-4, 4-parameter MDRD Study equation; >60, eGFR values >60 ml/min/1.73 m² not reported; >90, eGFR values >90 ml/min/1.73 m² not reported; Exact, exact eGFR value reported.




Fewer than half (45%) of surveyed laboratories that were reporting eGFR were not reporting eGFRs >60 ml/min/1.73 m² per the NKDEP guidelines.
Chart Explanation: Fewer than half of the laboratories (45%) who reported eGFR were not reporting values >60 ml/min/1.73 m², as recommended by NKDEP due to increased imprecision and bias at these higher levels. Of the remaining laboratories, 6% were reporting up to 90 ml/min/1.73 m², 39% were reporting the exact value of eGFR, and 11% did not know their laboratory’s reporting convention. Finally, among the laboratories that did not report eGFR at the time of the survey, 59% are not considering reporting eGFR (whereas only 29% are considering eGFR reporting).
The National Kidney Disease Education Program (NKDEP) performed a survey of 6,350 representative U.S. laboratories (including physician office, hospital, independent, community clinic, health fair, insurance, public health, and other laboratories) regarding their serum creatinine and eGFR reporting practices in 2006-2007. As with any survey, there may be bias created by differential responses due to characteristics of respondents.

In the period October 2006-February 2007, the NKDEP (http://www.nkdep.nih.gov/) performed their own survey of 6,350 representative U.S. laboratories (including physician office, hospital, independent, community clinic, health fair, insurance, public health, and other laboratories) regarding their serum creatinine and eGFR reporting practices. The 10-item questionnaire included the following questions: “Does your lab report serum creatinine values for adults (18 years and older)?” (yes/no/not sure); “How many serum creatinine tests did your lab perform in 2005?”; “Does your lab ever report estimated glomerular filtration rates (eGFR) with serum creatinine determinations?”; (yes/no/not sure) “Under what circumstances does your lab report eGFR?” (with all measured serum or plasma creatinine determinations/only when specifically requested/other); “Which estimating equation do you use for your reports?” (4-parameter MDRD Study equation/6-parameter MDRD Study equation/Cockcroft-Gault/not sure/other; and “When reporting eGFR, at what point do you assign a ‘greater than’ (>) value?” (60 ml/min/1.73 m²/90 ml/min/1.73 m²/never (we always report an exact number)/other). A total of 4,002 laboratories responded to the survey (63% response rate), and 2,493 of these 4,002 laboratories responded that their laboratory reported serum creatinine and subsequently provided information on eGFR reporting.
FieldData
Description of MeasureLaboratory reporting of eGFR
Data SourceNational Kidney Disease Education Program
Type of Data SourcePrivate
Data SetLaboratory survey results
Health Care System DataNo
Regional or National?National
Demographic GroupRepresentative sample of accredited laboratories in the CMS CLIA database with a specialty in routine chemistry testing who responded to survey
NumeratorLaboratories that reported eGFR with serum creatinine
DenominatorRepresentative sample of accredited laboratories that responded to survey
Glomerular filtration rateMethod of estimation of GFR varied by laboratory and was part of survey
Primary Data Source IndicatorProportion of U.S. laboratories that reported eGFR with serum creatinine
Primary Indicator Method of MeasurementSurvey
Frequency of Measurement (Primary)Once (cross-sectional)
U.S. Region Covered by Primary VariableAll
Period Currently Available2006–2007
Pending DataUnknown
Additional Data Items of InterestMethod of estimation, reporting standards, frequency of reporting, type of laboratory, volume of testing
Limitations of IndicatorOnly those laboratories of the sample that responded to the survey were included; recall bias
Analytical ConsiderationsMethod, standards & frequency can only be obtained within those reporting serum creatinine and eGFR
References and Sources:
  • Accetta NA, Gladstone EH, DiSogra C, Wright EC, Briggs M, Narva AS. Prevalence of estimated glomerular filtration rate (eGFR) reporting among US clinical laboratories. Am J Kidney Dis. 2008;52(4):778-787.
    http://www.ncbi.nlm.nih.gov/pubmed/18676076
Suggested Citation:
Centers for Disease Control and Prevention. Chronic Kidney Disease Surveillance System—United States.
website. http://www.cdc.gov/ckd