CDC Surveillance System: Incidence of Children and Adolescents with Reported ESRD per Million

^b As per the release of the 2015 USRDS report, the age range categories will be defined as shown above. Children and adolescents will be defined as individuals with less than or equal to 21 years of age from this point forwards.

The adjusted incidence of U.S. ESRD among 0- to 21-year-olds in 2016-2018 was 16 cases per million U.S. children and adolescents.

Chart Explanation:

During 2016-2018, 4,363 patients who were ≤21 years of age reported the occurrence of treatment for ESRD in the United States. Adolescents (18 to 21 years) had the highest adjusted incidence of treated ESRD (31 cases per million) of the age groups while Native Hawaiian/Pacific Islanders had the highest total adjusted incidence compared to whites, African-Americans, Asians and Native Americans (70 vs. 15, 23, 12, and 10 cases). Male children and adolescents had a higher adjusted incidence rate compared to females (18 vs. 14 cases per million respectively).

The United States Renal Data System (USRDS) is a national registry of all patients treated for end-stage renal disease (ESRD) in the United States. It is sponsored by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK) and the Centers for Medicare & Medicaid Services (CMS) that reports prevalence of all treated ESRD in the United States. U.S. population denominators are determined through U.S. Census data. Tables from the USRDS annual report (United States Renal Data System, 2020) are publicly available for download.

Field	Data
Description of Measure	Incidence of treated end-stage renal disease (stage 5) in children & adolescents
Data Source	USRDS (NIDDK/CMS)
Type of Data Source	Public
Data Set	USRDS
Health Care System Data	No
Regional or National?	National
Demographic Group	Medicare-eligible U.S. citizens <22 years old with ESRD-related claims with known age, race/ethnicity, and gender
Numerator	Number of patients <22 years old with new diagnosis of ESRD
Denominator	U.S. resident population <22 years old from U.S. census from corresponding year
Definition of CKD	Stage 5, <15 ml/min per 1.73 m² with Medicare-eligibility for ESRD-related treatment
Primary Data Source Indicator	Number of patients reported to have a new diagnosis of ESRD, as indicated by first treatment (dialysis or functioning transplant)
Primary Indicator Method of Measurement	Claims
Frequency of Measurement (Primary)	Annual (cross-sectional)
U.S. Region Covered by Primary Variable	All
Period Currently Available	2006–2018
Additional Data Items of Interest	Year, age (from date of birth), race/ethnicity (from Medicare 2728 form), gender (from Medicare 2728 form), assigned cause of ESRD (from Medicare 2728 form), BMI
Limitations of Indicator	Only those who are Medicare-eligible are captured and eligibility may be delayed; changes in 2728 form
Analytic Considerations	Denominators change with missing stratification variables

References and Sources:

United States Renal Data System. 2020 USRDS Annual Data Report: Epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2020.

Suggested Citation:

Centers for Disease Control and Prevention. Chronic Kidney Disease Surveillance System—United States.
website. http://www.cdc.gov/ckd