Automatic laboratory reporting of eGFR with serum creatinine has been increasing over time; overall, 92% of surveyed College of American Pathologists (CAP)-accredited laboratories reported eGFR with serum creatinine in 2019 (vs. 89% in 2017).
In 2019, the percentage of laboratories accredited by the College of American Pathologists (CAP) reporting eGFR with serum creatinine measurements slightly increased. A total of 92% of the 6,217 laboratories that responded reporting eGFR with serum creatinine, with a slight 3% increase from 2017 but a substantial increase from 2005 when only 20% of survey respondents reported eGFR with creatinine.
The College of American Pathologists (CAP) performs regular surveys of CAP-accredited laboratories. In June of 2003, 2005, and 2007, annually from 2008 to 2013, 2017, and 2019 CAP included in its General Chemistry Survey, in which all CAP-accredited laboratories that performed routine chemistries (representing an estimated 80% or more of U.S. laboratories performing routine chemistries) were sent a questionnaire regarding their eGFR reporting practices (2019 n=6,217 responding laboratories).
In a supplemental survey, laboratories were asked “Does your institution report an estimated Glomerular Filtration Rate (GFR) based on a serum or plasma creatinine measurement without measuring urine creatinine?” (yes/no); “If yes, when do you report the estimated GFR?” (with all measured serum or plasma creatinine determinations/only when specifically requested/other); and “If your institution reports an estimated GFR, what formula is used?” (4-parameter MDRD Study equation/IDMS-traceable 4-parameter MDRD Study equation (added 2011)/6-parameter MDRD Study equation/CKD-EPI equation (added 2011)/Cockcroft-Gault/not sure/other).
In the creatinine accuracy calibration survey, which is purchased by laboratories for self-assessment, CAP asked participants to state their creatinine calibration method: IDMS-traceable versus traditional calibration. Note that manufacturers were polled in June 2009; it was found that all major global manufacturers are currently only distributing IDMS-traceable serum creatinine methods (as of the end of 2009) in all markets they serve. All existing lots of older calibration reagents should have been used up during 2010 (exceptions: the Siemens Dimension/Vista Jaffe method, which will continue with its current calibration traceability and the Nova Biomedical blood gas instrument creatinine measurement). Some smaller manufacturers were not represented in the inquiry but all major North American and global manufacturers responded (Miller, 2009; http://nkdep.nih.gov/labprofessionals/Clinical_Laboratories.htm).
General Chemistry Survey results
Bi-annual to 2007, annual from 2008 to 2013, and then 2017 and 2019 (cross-sectional) for chemistry survey