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Prevalence of CKD Stages 3-5 in the Military Health System

Prevalence of CKD Stages 3-5 in the Military Health System

The prevalence of chronic kidney disease (CKD) stages 3–5 within the Military Health System (MHS) has remained low, with 2% of service members and their dependents having eGFR below 60 ml/min/1.73 m2. Prevalence trended lower between 2009 and 2015, with 1.7% of service members and their dependents having CKD stages 3–5 in 2015. Prevalence of CKD stages 3–5 is much higher among older service members and dependents. Female adults show a slightly higher prevalence (1.9% vs. 1.5% in 2015). Non-hispanic Black adults showed the highest prevalence of CKD stages 3–5 compared to other racial/ethnic groups.

Data Source: DoD-MHS

To view the prevalence of CKD stages 3–5 in MHS by risk categories, select from the drop-down menu below. Risk categories include Age, Sex, and Race.


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The majority of service members and their dependents did not have eGFR estimates (73%) and were assumed to not have eGFR < 60 ml/min/1.73m2; therefore, prevalence may be underestimated. Data are not adjusted.

The US Department of Defense Military Health System (MHS) provides comprehensive primary and specialty care for more than 9.6 million active-duty personnel and military retirees and their families worldwide. The MHS Data Repository (MDR) is the administrative claims database for all care received through MHS, including direct care received in military treatment facilities and purchased care received in civilian treatment facilities. The MDR does not capture health care delivery in combat zones or care received in the VHA system. All patients were in the TRICARE Prime managed care option. Data are from both the direct care (military facilities) and private care (private facilities through TRICARE coverage) systems.

De-identified patient data were obtained from the MHS data repository. Data contain both the estimated glomerular filtration rate (eGFR) definition of chronic kidney disease (CKD) and claims-based CKD defined by using ICD-9-CM and ICD-10-CM codes diagnosis codes with at least one inpatient or two outpatient CKD diagnoses. To be included in analyses, service members and their dependents had to have at least one inpatient or outpatient record during the fiscal year (October 1 to September 30). Data cells with 10 or fewer patients were suppressed.

Disclaimer: The views expressed are those of the authors and do not reflect the official policy of the Uniformed Services University, Departments of Army/Navy/Air Force, Department of Defense, Centers for Disease Control and Prevention, Department of Health and Human Services, or US government.

FieldData
Description of Measure

Prevalence of CKD stages 3–5 in MHS.

Data Set

US Department of Defense MHS Data Repository (MDR). MDR source files: CAPER (direct care outpatient claims), SIDR (direct care inpatient claims), TED-NI (purchased care outpatient claims), TED-I Header (purchased care inpatient claims), and VM6BEN (demographic information from the Defense Enrollment Eligibility Reporting System).

Population

Service members and their dependents in MHS.

Years Included

2009–2015.

Numerator

Service members and their dependents with eGFR < 60 ml/min/1.73m2 for at least 90 days.

Denominator

Service members and their dependents with at least one outpatient or inpatient visit during the fiscal year (October 1 to September 30).

Definition of CKD and CKD Stage

CKD is defined by estimated glomerular filtration rate (eGFR): stage 3: eGFR 30–59 ml/min/1.73 m²; stage 4: eGFR 15–29 ml/min/1.73 m²; stage 5: eGFR < 15 ml/min/1.73 m² for at least 90 days, excluding dialysis or transplant patients.

Estimated glomerular filtration rate (eGFR)

Based on the CKD-EPI equation for calibrated creatinine: eGFR=141 x [min(serum creatinine in mg/dL) /κ, 1)]**α x [max(serum creatinine/κ, 1)]**-1.20 x 0.993**age x (1.018 if female) x (1.159 if a Black person).

κ = 0.7 if female and 0.9 if male
α = -0.329 if female and -0.411 if male
** = raise to the power

Serum Creatinine

Laboratory measurements taken during MHS visits.

Diabetes

Diabetes status determined by at least one inpatient or two outpatient diagnoses based on the presence of an ICD-9-CM code (250.xx, 357.2, 336.41, 362.01, 362.02;  

x and xx stand for all the codes within the main diagnosis).

Hypertension

Hypertension status determined by at least one inpatient or two outpatient diagnoses based on the presence of an ICD-9-CM code (401.x through 405.x; x stands for all the codes within the main diagnosis).

Limitations of Indicator

Data is only available through 2015. The majority of service members and their dependents did not have eGFR estimates (73%) and were assumed to not have eGFR < 60 ml/min/1.73m2; therefore, prevalence may be underestimated.

Analytical Considerations

Service members and their dependents in MHS tend to be younger and healthier than the general population. Therefore, testing for serum creatinine and UACR are performed less frequently than in other health care systems.


eGFR Formula Disclaimer
At the time of the last data update in summer 2022, the race-free eGFR formula was newly recommended and impact on health outcomes is underway. To avoid inconsistent results caused by different formulae, stakeholders continued using the eGFR formula with race during this transition. Since then, comparisons have been made. The estimates for the current website launch are still based on analyses using the eGFR formula with race, however plan is to use race-free eGFR formula for the next data update and upcoming website launch in fall 2023.