Hospitalizations for Lower Extremity Amputations in Adults with Diabetes, United States

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Sex Age-adjusted Rate
(per 1,000)
Overall 4.9
Males 6.6
Females 3.0
Sex Age Group
(in years)
Lower Extremity Amputations Estimated Events
Attributable to DiabetesReports the estimated number of hospitalizations that are attributed to diabetes, which can be interpreted as the number of hospitalizations that would be reduced if diabetes were eliminated. The number is rounded to the nearest 10.
Total Events Crude Rate
(per 1,000)
95% Confidence Interval
Lower Limit Upper Limit
Overall 18-44 15,030 3.8 3.6 4.0 13,632
45-64 82,543 6.6 6.4 6.8 74,107
65-74 40,485 5.3 5.1 5.5 34,338
75+ 26,649 4.9 4.6 5.1 20,296
Total 164,814 5.6 5.5 5.7 142,927
Males 18-44 9,747 4.9 4.5 5.3 9,129
45-64 60,317 9.3 8.9 9.6 54,552
65-74 28,992 7.5 7.1 7.8 24,542
75+ 17,817 6.7 6.3 7.1 14,088
Total 116,778 7.8 7.5 8.0 102,741
Females 18-44 5,084 2.6 2.3 2.8 4,503
45-64 21,955 3.7 3.5 3.9 19,556
65-74 11,543 3.1 3.0 3.3 9,796
75+ 8,728 3.1 2.9 3.3 6,205
Total 47,371 3.3 3.2 3.4 40,188

Data Source: Agency for Healthcare Research and Quality, Healthcare Cost and Utilization Project, State Inpatient Databases.

Note: Although the national estimates are reported at the annual level, the years of data vary across states (2019-2021).

Race-Ethnicity Lower Extremity Amputation as First-Listed Diagnosis
Total Events Crude Rate
(per 1,000)
95% Confidence Interval
Lower Limit Upper Limit
Non-Hispanic White 77,453 4.47 4.40 4.56
Non-Hispanic Black 26,801 7.19 6.93 7.46
Hispanic 16,108 5.21 4.95 5.50
Non-Hispanic Other Races 6,665 3.77 3.55 4.02

The non-Hispanic Other Races group includes races other than White and Black and people of more than one race.

Data Source: Agency for Healthcare Research and Quality, Healthcare Cost and Utilization Project, State Inpatient Databases.

Data from Alabama, California, Connecticut, Idaho, Louisiana, New Hampshire, and Ohio are not included in the national estimates because State Inpatient Databases for these states were not available.

Note: Although the national estimates are reported at the annual level, the years of data vary across states (2019-2021).

Rural and Urban Areas Lower Extremity Amputation as First-Listed Diagnosis
Total Events Crude Rate
(per 1,000)
95% Confidence Interval
Lower Limit Upper Limit
Rural 10,993 4.89 4.71 5.08
Urban 118,668 5.01 4.92 5.09

Data Source: Agency for Healthcare Research and Quality, Healthcare Cost and Utilization Project, State Inpatient Databases.

Data from Alabama, California, Connecticut, Idaho, Louisiana, New Hampshire, and Ohio are not included in the national estimates because State Inpatient Databases for these states were not available.

Note: Although the national estimates are reported at the annual level, the years of data vary across states (2019-2021).

Counties were categorized as rural or urban following the 2013 National Center for Health Statistics Urban-Rural Classification Scheme. Urban counties include large central metropolitan, large fringe metropolitan, medium metropolitan, small metropolitan, and micropolitan counties. Rural counties include noncore counties (i.e., nonmetropolitan counties that do not qualify as micropolitan).

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